Over two years into the pandemic and over a year since the COVID-19 vaccinations rolled out, millions of people are still nursing themselves in the aftermaths as they recover from spike protein injuries, whether it be through COVID-19 or vaccinations.
Many doctors put together recommendations on treating long COVID and vaccine injuries based on clinical observations and published research.
However, a smaller group of people may not respond to the typical first line treatments or may respond with remaining unresolved conditions.
That is when doctors bring out treatments considered “second-line.” These treatments are typically more aggressive and targeted, meaning that it could work very well but for a smaller group of people. They can also be more expensive and harder to self-administer.
Spike Protein Injury: A Systemic Disease Requiring Systemic Treatment
Saleeby, along with other doctors treating spike protein injury including Dr. Paul Marik and Dr. Pierre Kory, both previously interviewed by The Epoch Times, understand spike injury as a syndrome rather than disease since it is precipitated by dysfunctions in many overlapping pathways.Dr. Paul Marik was a former professor of medicine and the chief of pulmonary and critical care medicine at Eastern Virginia Medical School. Dr. Pierre Kory was the former chief of the critical care service and medical director of the Trauma and Life Support Center at the University of Wisconsin.
- Reduced Autophagy: The first thing the spike protein does is that it blocks autophagy. This prevents infected cells from clearing out and dispelling the spike protein, leading to many of the downstream problems. Therefore a major focus of the first line treatment is to reactivate autophagy and clear out the spike protein hidden away in the affected cells.
- Mitochondrial Dysfunction: In cells, spike protein cause mitochondrial dysfunction by directly affecting the mitochondria or causing stress to its environment. Mitochondrial dysregulation reduces energy production for the cell and can also result in production of damaging oxidative species, both of which can lead to cell stress, fatigue, and cell death.
- Reactivated or Persistent Infections: Spike proteins also downregulate immune cells, with studies showing dysregulation in T cells and innate cell responses. A fall in immunity often correlates with opportunistic infections and viral reactivation, with many studies reporting a relapse of latent viruses following vaccination or infection.
- Mast Cell Response: Spike proteins can trigger the activation of mast cells. These immune cells play major roles in allergic responses by releasing histamine. Histamine release contribute to inflammation with patients presenting with symptoms of fever, headaches, swelling, and many other debilitating conditions.
- Blood Clot Formation: Studies found that in the bloodstream, spike protein can bind to blood-clotting proteins such as fibrinogen and form abnormal blood clots. Apart from inflammation, these blood clots can lead to blood vessel blockage and tissue damage, precipitating to stroke and heart attacks.
- Cancer: Studies found that cells exposed to the spike protein through viral genes or protein exposure would increase in DNA damage markers, indicative of DNA damage. This can lead to dysfunctional, potentially cancerous cells if these cells are not killed by the immune system.
- Autoimmunity: Spike protein also share many similarities with human proteins and tissues, so antibodies that attack spike protein may also bind to human tissues and proteins, leading to self-attack.
Methylene Blue
Methylene blue (MB) has been recommended by many doctors as a priority second line treatment due to its antiviral, anti-inflammatory, and antioxidizing properties.“It’s kind of an interesting compound,” said Saleeby. MB started its life as an industrial dye for textiles, it was later used to stain cells under the microscope, and scientists noticed that parasites would die when stained with MB.
“So they found heavy anti-parasitic properties.” said Saleeby.
MB has been used to treat malaria, urinary tract infections, and is the most well known for its use in methemoglobinemia, a condition where the red blood cells cannot carry oxygen due to the loss of an electron on its iron group.
Though recommended as a second line treatment for spike protein-induced diseases, MB actually carries first line spike injury treatment functions.
It is recommended to alleviate neurological symptoms related to brain fog, fatigue, memory, and cognition, which are common spike injury symptoms.
Additionally, MB’s function as an antioxidant also enables it to contribute to anti-aging.
The product is highly accessible, however people wanting to take MB should take care that they are using pharmaceutical grade MB rather than industrial or research grade.
“You can get the dye at the industrial level that they use as a dye which could be contaminated with heavy metals and a lot of other junk,“ said Saleeby, “Then there’s research grade, to be used in vitro and things for research.”
The safest grade are those that meet the standard of the United States Pharmacopeial (USP) Convention.
“There are a couple of places you can get [purchase] that or you can have it compounded at a compounding pharmacy, [the pharmacist can] just write a prescription for say, a 30 ml bottle of 1 percent methylene blue solution and that will be for human consumption or veterinary consumption.” said Saleeby.
Methylene blue is not recommended for pregnant and breastfeeding women and people with G6PD deficiency. For people taking selective serotonin reuptake inhibitors (SSRI), methylene blue can interact with SSRIs, potentially leading to serotonin syndrome—a critical condition.
Oxytocin
Colloquially known as the love hormone, oxytocin is often associated with happiness, love, and emotional bonding.However, oxytocin does not only affect the brain but also has receptors in heart, kidney, uterus, breast, and the testes, and therefore plays much bigger roles than contributing to happiness.
Saleeby found that oxytocin was very effective for people with neuropsychiatric problems such as depression and anxiety. It also helped to improve emotional relationships.
“With the lockdown, you had a lot of social distancing and people forgot how to socially interact with each other and that’s problematic,” said Saleeby, “this is actually helpful in rebounding as a bonding, reestablishing humans and social connections.”
He also prescribes it for people with reproductive problems such as erectile dysfunction in males and anorgasmia in females. He also uses oxytocin as a last resort treatment to improve bone health when common treatments such as calcium, vitamin D, and vitamin K2 all fail.
“It’s probably one of the most ignored hormones out there,” said Saleeby.
Oxytocin is rarely prescribed, since it needs to be refrigerated to prevent degradation, regardless of whether it is in powder or solution, making it less practical for daily use. Oxytocin nasal sprays found in supermarkets and online stalls are thus likely not effective, Saleeby cautioned.
Yet the multifaceted roles oxytocin plays can often make up for its logistic annoyances.
Oxytocin could reverse this action.
Despite these benefits, “a lot of [oxytocin’s mechanism of action] is poorly understood. We just know that it works, especially with behavioral things like bonding,” said Saleeby.
Adaptogens
Saleeby also recommends nutraceuticals such as vitamins and adaptogens as both first and second line treatments for spike protein injuries.Adaptogen are herbs that can work as medicine; this includes curcumin, certain types of mushrooms, and various plants.
Nutraceuticals
Many nutraceuticals such as magnesium, vitamin D, vitamin C, and omega-3 oils are also recommended as second line treatments by doctors to improve individuals’ immune function and reduce inflammation.Both vitamin D and omega-3 are also recommended for hair loss following vaccination.
For all vitamin nutraceuticals, Saleeby recommended getting pharmaceutical grade supplements rather than easily accessible ones from the supermarkets or pharmacies.
“I would stick with pharmaceutical grade vitamins in general, 90 percent of the stuff you get over the counter is pretty much garbage,” said Saleeby. “Ninety percent of the fish oil that you get over the counter is what’s leftover from making the pharmaceutical grade.”
“You can’t go wrong if you use one of these high end pharmaceutical grade companies.”